Fractional Excretion Of Sodium Interpretation
The fractional excretion of sodium is the percentage of the sodium filtered by the kidney which is excreted in the urine. This is an unprecedented time.
Is it a prerenal cause decreased perfusion acute tubular necrosis atn or a post renal cause obstruction.
Fractional excretion of sodium interpretation. This study was performed to determine the influence of the glomerular filtration rate gfr sodium intake. In clinical use the fractional excretion of sodium can be cal. The fractional excretion of sodium fena measures the percent of filtered sodium that is excreted in the urine.
Fena is greater than 1 and usually greater than 3 with acute tubular necrosis and severe obstruction of the urinary drainage of both kidneys. The fractional excretion is calculated by multiplying urinary sodium concentration by the plasma creatinine concentration then dividing by the urinary creatinine concentration multiplied by the plasma sodium concentration. It is measured in terms of plasma and urine sodium rather than by the interpretation of urinary sodium concentration alone as urinary sodium concentrations can vary with water reabsorption.
In most normal subjects the fractional excretion of sodium is usually less than 1 percent but may be raised with an increase in salt intake. In acutely azotemic patients a low fractional excretion of sodium usually indicates a prerenal process that is responsive to volume repletion. The fractional excretion of sodium fena determines if renal failure is due to pre renal intrinsic or post renal pathology.
To accurately interpret fena patients should not have recently received diuretics. Definition nci the percentage of the total sodium filtered by the kidney that is excreted in the urine. It is the dedication of healthcare workers that will lead us through this crisis.
This calculation is widely used to help differentiate prerenal disease decreased renal perfusion from acute tubular necrosis atn as the cause of acute kidney injury aki formerly called acute renal failure. The fractional excretion of sodium fena has been reported to be of value in determining the cause of acute kidney injury aki 1 2. Described misapplications of commonly used kidney equations including fena and focused on the application and caveats of fena during aki.
The fractional excretion of sodium fena may be helpful in establishing the cause of acute renal failure. Fractional excretion of sodium fena utilizes urine chemistry to distinguish between different causes of acute kidney injury aki. Therefore the urinary and plasma concentrations of sodium must be compared to get an accurate picture of kidney clearance.
Calculate the fractional excretion of sodium given the serum and urine sodium and the serum and urine creatinine. In the setting of acute renal failure a fractional excretion of sodium fe na 1 suggests a prerenal state while a value 1 is suggestive of atn. These rules are not absolute however.
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